The Efficacy of Misoprostol Plus Vasopressin Versus Vasopressin Alone on Surgical Outcomes Through Minimally Invasive Myomectomy: Research Protocol
Keywords: leiomyoma, fibroids, laparascopy, blood loss, misoprostol, myomectomy
AbstractTo compare the effect of perivascular vasopressin with a combination of rectal misoprostol plus perivascular vasopressin on blood loss reduction during minimally invasive myomectomies, a double-blind randomized clinical trial it designed to be conducted in Shiraz, Iran in 2015. The primary outcomes of the study include; blood loss during surgery and hemoglobin (Hb) drop after surgery extracting the baseline and 6-hour post-surgery serum hemoglobin levels. The secondary outcomes of the study include; duration of operation; surgical complications; post-operative complications; hemodynamic changes during surgery, administration of other uterotonic agents; and post-operative fever.
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